|Present||Assistant Professor, Nova Southeastern University ‐ College of Engineering and Computing|
Professional Service and Affiliations
|2017 - Present||Reviewer, Chancellor’s Faculty Research and Development Grant, Nova Southeastern University||2017 - Present||NSU CEC representative for ASEE, Nova Southeastern University||2017 - Present||NSU Honors College Faculty Committee Member, Nova Southeastern University||2016 - Present||Member of Research Standing Committee; College of Engineering and Computing, Nova Southeastern University||2016 - Present||Member, Faculty Advisory Council, CEC, Nova Southeastern University||2010 - Present||Tissue Engineering and Regenerative Medicine International Society (TERMIS), Nova Southeastern University||2009 - Present||Biomedical Engineering Honors Society (AEMB), Nova Southeastern University||2007 - Present||Biomedical Engineering society (BMES), Nova Southeastern University||2006 - Present||Florida Engineering Society (FES), Nova Southeastern University||2016 - 2016||Editorial Board Member, Early Career Technical Conference, Nova Southeastern University|
|2014||Ph.D., Biomedical Engineering, Florida International University|
|2011||M.S., Biomedical Engineering, Florida International University|
|2009||B.S., Biomedical Engineering, Florida International University|
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Heart Valve Tissue Engineering: Mathematical Modeling for Bioreactor Studies Mathematics Colloquium Series (2017)
Mechanical conditioning has been shown to promote tissue formation in a wide variety of tissue engineering studies, but the underlying mechanisms by which external mechanical stimuli regulate cells and tissues are not fully understood. This ...
Relative Effects of Fluid Oscillations and Nutrient Transport in the In Vitro Growth of Valvular Tissues Cardiovascular Engineering Technology (2016)
Engineered valvular tissues are cultured dynamically, and involve specimen movement. We previously demonstrated that oscillatory shear stresses (OSS) under combined steady flow and specimen cyclic flexure (flex-flow) promote tissue formation. However, localized efficiency of specimen ...
Marrow Stem Cell Differentiation for Valvulogenesis via Oscillatory Flow and Nicotine Agonists: Unusual Suspects? Journal of Long-Term Effects of Medical Implants (2015)
Fluid-induced oscillatory shear stress (OSS) and nicotine are known antagonists in cardiovascular disease. However, from a regenerative medicine standpoint, we hypothesized that these parameters may support the cell differentiation of bone marrow mesenchymal stem cells ...
Computational Simulations Predict a Key Role for Oscillatory Fluid Shear Stress in de Novo Valvular Tissue Formation Journal of Biomechanics (2014)
Previous efforts in heart valve tissue engineering demonstrated that the combined effect of cyclic flexure and steady flow on bone marrow derived stem cell-seeded scaffolds resulted in significant increases in engineered collagen formation [Engelmayr et ...
Oscillatory Shear Stress Created by Fluid Pulsatility versus Flexed Specimen Configurations Computer Methods in Biomechanics and Biomedical Engineering (2014)
Oscillatory shear stress (OSS), caused by time-varying flow environments, may play a critical role in the production of engineered tissue by bone marrow-derived stem cells. This is particularly relevant in heart valve tissue engineering (HVTE), ...
Applicability of the Taguchi Method to Mechanobiology-Based Experiments Journal of Validation Technology (2013)
Design of experiments (DOE) methods are very commonly used for process validation. In this study, we employed the Taguchi approach in order to develop an optimal process for the maximization of oscillatory shear stress environments ...
Protocol for Relative Hydrodynamic Assessment of Tri-Leaflet Polymer Valves Journal of Visualized Experiments (2013)
Limitations of currently available prosthetic valves, xenografts, and homografts have prompted a recent resurgence of developments in the area of tri-leaflet polymer valve prostheses. However, identification of a protocol for initial assessment of polymer valve ...
Books and Book Contributions (1)
Computational Fluid Modeling of Heart Valves Computational Bioengineering (2017)
Healthy heart valves are essential for proper blood circulation. Their role is to ensure unidirectional blood flow in the circulatory system. They consist of different tissue layers and are capable of adapting and remodeling their ...