Article
Synthesis and characterization of self-assembled block copolymer templated calcium phosphate nanocomposite gels
Journal of Materials Chemistry
Document Type
Article
Disciplines
Publication Date
1-1-2007
DOI
10.1039/b613760a
Abstract
Self-assembled macroscale calcium phosphate-copolymer nanocomposite gels were prepared using a bottom-up approach from aqueous solutions. Amphiphilic block copolymer micelles in aqueous solutions were used as templates for the growth of calcium phosphate nanocrystals and then allowed to self-assemble in solution to form thermoreversible nanocomposite gels. NMR and XRD showed that calcium phosphate precipitation in a Pluronic® F127 copolymer gel resulted in a disordered brushite phase while the calcium phosphate-poly(2- diethylaminoethyl methacrylate) (PDEAEM) modified Pluronic® F127 pentablock copolymer nanocomposite contained the same brushite phase along with a calcium dihydrogen phosphate second phase. TEM, SAXS, and NMR experiments confirmed that the calcium phosphate precipitated on and interacted with the polymer micelles forming an organized network of ∼20 nm diameter nanospheres. The resulting polymer-calcium phosphate nanocomposite gels contained between 6.5 and 15 weight percent calcium phosphate, which could be controlled by manipulating the pH of the constituent solutions.
Copyright Owner
The Royal Society of Chemistry
Copyright Date
2007
Language
en
File Format
application/pdf
Citation Information
D. Enlow, A. Rawal, Mathumai Kanapathipillai, Klaus Schmidt-Rohr, et al.. "Synthesis and characterization of self-assembled block copolymer templated calcium phosphate nanocomposite gels" Journal of Materials Chemistry Vol. 17 Iss. 16 (2007) p. 1570 - 1578 Available at: http://works.bepress.com/mallapragada_surya_k/9/
This article is from Journal of Materials Chemistry 17 (2007): 1570, doi: 10.1039/b613760a.