A Brownfields Area-Wide Plan is created for a key portion of Philadelphia’s Lower North Delaware Industrial District. The brownfields challenges in the project are representative of both location-specific factors and issues typical of brownfield redevelopment. One hundred and fifty years of industrial history, from coal to textile or food distribution, cannot help but leave a trace. Locational factors including high vacancy rates, weak market forces, and former industrial uses highlight the classic brownfields challenges of financial barriers, liability issues, and cleanup considerations. The coalescence of these types of difficulties significantly impacts the economic, social, public health, and environmental justice concerns within the project area, and significantly hampers development. This plan summarizes the cleanup and reuse implementation strategies for the catalyst sites using information obtained through research into community engagement, prioritization, existing conditions, partnerships, and potential resources.