The intermediate-temperature performance of extracted asphalt binders (EABs) is altered when recycled asphalt shingles (RAS) and/or reclaimed asphalt pavement (RAP) are included in asphalt mixes. This happened as a result of the RAP's aged asphalt binder and the RAS's oxidized air-blown asphalt. Thus, the rheological properties of EABs from field cores were examined at intermediate temperatures. The fatigue life and the Superpave fatigue cracking parameter were among the rheological properties. Thermogravimetric analysis and Fourier transform infrared were used to analyze EABs' thermal and chemical characteristics, respectively. The relationships between EABs' fatigue cracking resistance, thermal, and chemical characteristics were scrutinized. Ages of mixes, percentages of RAP and/or RAS, and intermediate performance grade (PG) temperatures of virgin asphalt binders (VABs) controlled the resistance of EABs to fatigue cracking. Considering VABs with the same intermediate PG temperatures, EABs from older mixes with higher RAS percentages had higher resistance to fatigue cracking than those from younger mixes with lower RAP percentages. When RAP percentages in asphalt mixes were increased, EABs' resistance to fatigue cracking deteriorated. Thermal and chemical analyses along with rheological characteristics are suggested as indicators of EABs' intermediate-temperature performance.