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Article
Spindle Positioning: Actin Mediates Pushing and Pulling
Current Biology (2009)
  • M Bezanilla
  • P Wadsworth
Abstract

To divide asymmetrically, the mitotic spindle is moved from the cell center to the cortex, a process that requires astral microtubules and the microtubule-based motor dynein. New work examining spindle positioning in large oocytes shows that in these cells actin and actin polymerization plays a key role.

Disciplines
Publication Date
January 1, 2009
Publisher Statement
DOI: 10.1016/j.cub.2008.12.026
Citation Information
M Bezanilla and P Wadsworth. "Spindle Positioning: Actin Mediates Pushing and Pulling" Current Biology Vol. 19 Iss. 4 (2009)
Available at: http://works.bepress.com/magdalena_bezanilla/7/