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Article
Depot medroxyprogesterone acetate and bone mineral density in adolescents - The black box warning: A position paper of the society for adolescent medicine
Journal of Adolescent Health
  • B. A. Cromer
  • D. Scholes
  • A. Berenson
  • T. Cundy
  • M. Kathleen Clark, University of Iowa
  • A. M. Kaunitz
Document Type
Article
Peer Reviewed
1
Publication Date
1-1-2006
NLM Title Abbreviation
J Adolesc Health
PubMed ID
16857545
DOI of Published Version
10.1016/j.jadohealth.2006.03.011
Abstract
The purpose of this Position Paper is to review the published Black Box Warning regarding depot medroxyprogesterone acetate (DMPA) and bone loss as it relates to adolescent girls. The scientific findings that prompted the Food and Drug Administration to issue the warning are reviewed and the following additional issues are considered: (1) likely low risk of fracture related to DMPA use, (2) evidence of at least partial recovery after discontinuation of the method, and (3) the need to balance the physical, social and economic cost of adolescent pregnancy versus the immediate and long-term impact of DMPA on bone. A list of clinical guidelines is included, the main recommendation of which is to continue prescription of DMPA, with counseling about the risks and benefits, in most of the adolescent population desiring to use this contraceptive method. (c) 2006 Society for Adolescent Medicine. All rights reserved.
Published Article/Book Citation
Journal of Adolescent Health, 39:2 (2006) pp.296-301. DOI:10.1016/j.jadohealth.2006.03.011.
Disciplines
Citation Information
B. A. Cromer, D. Scholes, A. Berenson, T. Cundy, et al.. "Depot medroxyprogesterone acetate and bone mineral density in adolescents - The black box warning: A position paper of the society for adolescent medicine" Journal of Adolescent Health Vol. 39 Iss. 2 (2006) p. 296 - 301 ISSN: 1054-139X
Available at: http://works.bepress.com/m_clark/11/