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Article
Characterization of an Avirulent Mutant of a Virulent Avian Escherichia coli Isolate
Avian Diseases (1994)
  • Lisa K. Nolan
  • Richard E. Wooley, University of Georgia
  • Catherine W. Giddings
  • john Brown, University of Georgia
Abstract
A virulent, complement-resistant avian Escherichia co/lisolate and its avirulent, complement-sensitive, transposon-insertion mutant were compared for the purpose of revealing structures associated with complement resistance. Both had a smooth lipopolysaccharide layer, contained traT, and lacked a capsule, but the mutant possessed a 16.2-kilodalton outer-membrane protein (OMP) not present in the wild-type. This protein may be the product of a coding region interrupted by transposon insertion. Such results suggest that an OMP greater than 16.2 kilodaltons in size may be responsible for the complement resistance and virulence of this wild-type E. coli.
Publication Date
March, 1994
Publisher Statement
Copyright 1994 American Association of Avian Pathologists. Posted with permission.
Citation Information
Lisa K. Nolan, Richard E. Wooley, Catherine W. Giddings and john Brown. "Characterization of an Avirulent Mutant of a Virulent Avian Escherichia coli Isolate" Avian Diseases Vol. 38 Iss. 1 (1994)
Available at: http://works.bepress.com/lisa_nolan/67/