A survey was conducted among library and information science (LIS) practitioners to examine the effect of the research methods course on LIS practitioners' work. Findings suggest the research methods course is a valuable component of the master's in library and information science (MLIS) program. Taking the research methods course increases LIS practitioners' research interest and assists them by helping them critically evaluate published literature and apply it at work, provide better assistance to library patrons, produce valid and reliable data to facilitate decision making, identify problems at work and design and implement studies to solve them, and write grants and for publication. Suggestions are made to improve the research methods curriculum and enhance the educational experience for LIS practitioners.