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Misclassification Simulation Extrapolation Method for a Weibull Accelerated Failure Time Model
Statistical Methods in Medical Research
  • Varadan Sevilimedu, Georgia Southern University, Jiann-Ping Hsu College of Public Health
  • Lili Yu, Georgia Southern University, Jiann-Ping Hsu College of Public Health
  • Hani Samawi, Georgia Southern University, Jiann-Ping Hsu College of Public Health
Document Type
Article
Publication Date
4-25-2023
DOI
10.1177/0962280223116824
Disciplines
Abstract

The problem of misclassification in covariates is ubiquitous in survival data and often leads to biased estimates. The misclassification simulation extrapolation method is a popular method to correct this bias. However, its impact on Weibull accelerated failure time models has not been studied. In this paper, we study the bias caused by misclassification in one or more binary covariates in Weibull accelerated failure time models and explore the use of the misclassification simulation extrapolation in correcting for this bias, along with its asymptotic properties. Simulation studies are carried out to investigate the numerical properties of the resulting estimator for finite samples. The proposed method is then applied to colon cancer data obtained from the cancer registry at Memorial Sloan Kettering Cancer Center.

Comments

Georgia Southern University faculty members, Lili Yu and Hani Samawi co-authored Misclassification Simulation Extrapolation Method for a Weibull Accelerated Failure Time Model.

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Citation Information
Varadan Sevilimedu, Lili Yu and Hani Samawi. "Misclassification Simulation Extrapolation Method for a Weibull Accelerated Failure Time Model" Statistical Methods in Medical Research (2023)
Available at: http://works.bepress.com/lili-yu/105/