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Presentation
Characterization of Polyethylene Glycol Modified Hemoglobins
American Physical Society March Meeting (2011)
  • G. Salazar
  • J. Barr
  • W. Morgan
  • Li Ma, Georgia Southern University
Abstract
Polyethylene glycol modified hemoglobins (PEGHbs) was characterized by liquid chromatography and fluorescence methods. We prepared four samples of two different molecular weight PEG, 5KDa and 20KDa, modified bovine and human hemoglobin. We studied the oxygen affinities, stabilities, and peroxidase activities of PEGHbs. We have related oxygen affinities with different degrees of modifications. The data showed that the modification on the beta subunits was less stable than that of the alpha subunits on the human Hb based samples especially. We also compared peroxidase activities among different modified PEGHbs. http://adsabs.harvard.edu/abs/2011APS..MARJ39010S
Disciplines
Publication Date
March 21, 2011
Citation Information
G. Salazar, J. Barr, W. Morgan and Li Ma. "Characterization of Polyethylene Glycol Modified Hemoglobins" American Physical Society March Meeting (2011)
Available at: http://works.bepress.com/li_ma/17/