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Copper-Catalyzed Allylic Substitution
Organotransition metal chemistry : from bonding to catalysis
  • Levi M. Stanley, Iowa State University
  • John F. Hartwig, University of Illinois - Urbana-Champaign
Document Type
Book Chapter
Disciplines
Publication Version
Published Version
Publication Date
1-1-2010
Abstract
Allylic substitution catalyzed by copper261- 269 is a transformation that is related to allylie substitutions catalyzed by other transition metals discussed previously in this chapter, but several features of copper-catalyzed allylations make them worth differentiating. First, copper-catalyzed allylic substitutions are conducted with different types of nucleophiles than most allylic substitutions catalyzed by other metals. Second, the regioselectivity of the copper-catalyzed reactions is typically different from that of reactions catalyzed by complexes of other metals, particularly of reactions catalyzed by complexes of palladium. Thus, this last section of the chapter describes studies on allylic substitution catalyzed by copper, with an emphasis on enantioselective examples.
Comments

This a chapter from Organotransition metal chemistry : from bonding to catalysis (2010): chapter 20.7, 999. Posted with permission.

Copyright Owner
University Science Books
Language
en
File Format
application/pdf
Citation Information
Levi M. Stanley and John F. Hartwig. "Copper-Catalyzed Allylic Substitution" Organotransition metal chemistry : from bonding to catalysis (2010) p. 999 - 1008
Available at: http://works.bepress.com/levi_stanley/17/