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About Lenora A. Pluchino, Ph.D.

Dr. Pluchino's research focuses on cancer therapeutics and prevention. Her main project involves designing novel therapeutic strategies for the treatment of metastatic bladder cancer. In vitro and in vivo mouse models are used to investigate the selectivity of chemotherapeutic agents and to identify drug synergy using two or more agents. Her research also involves understanding the mechanisms of environmental, dietary and tobacco-specific carcinogens on breast cell carcinogenesis with an emphasis on how multiple carcinogens act together to enhance sporadic breast cancer development. A major aim of her research is to use acquired cancer-associated properties as targeted endpoints to identify novel dietary chemopreventive agents that are capable of suppressing cellular carcinogenesis. Of particular interest are the roles of epithelial-to-mesenchymal transition, cancer stem-like cells and gene regulation by microRNAs.
Dr. Pluchino received her B.S. degree in Zoology with a minor in Chemistry from the State University of New York at Oswego in 2008. To further her education, she completed her doctoral degree in Genome Science and Technology with a specialization in Molecular Oncology at the University of Tennessee, Knoxville in 2014. She is currently undergoing post-doctoral training in the Department of Biomedical and Diagnostic Sciences at the University of Tennessee College of Veterinary Medicine.

Positions

Present Department of Biomedical and Diagnostic Sciences, University of Tennessee, Knoxville
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Present UT College of Veterinary Medicine, University of Tennessee, Knoxville
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Present Post-doctoral Research Associate, University of Tennessee, Knoxville
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Curriculum Vitae



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Contact Information

University of Tennessee
College of Veterinary Medicine
Department of Biomedical and Diagnostic Sciences, A307
2407 River Dr. Knoxville, TN 37996
Lab phone: (865) 974-5837

Email:


Publications (2)

Dissertation (1)

Abstracts (2)

Book Chapter (1)