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Selected Works of Lark Perez
Article
Characterization of gut microbiome and metabolome in Helicobacter pylori patients in an underprivileged community in the United States
bioRxiv (2021)
  • Brian E. White, Rowan University
  • John D. Sterrett, University of Colorado Boulder
  • Zoya Grigoryan, Lenox Hill Hospital
  • Lauren T. Lally, Thomas Jefferson University Hospital
  • Jared D. Heinze, University of Colorado Boulder
  • Hyder Alikhan, Rowan University
  • Christopher A. Lowry, University of Colorado Boulder
  • Lark Perez, Rowan University
  • Joshua DeSipio, Cooper University Hospital
  • Sangita Phadtare, Rowan University
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Abstract
Helicobacter pylori, a bacterium that infects approximately half of the world’s population, is associated with various gastrointestinal diseases, including peptic ulcers, non-ulcer dyspepsia, gastric adenocarcinoma, and gastric lymphoma. To combat the increasing antibiotic resistance of H. pylori, the need for new therapeutic strategies has become more pressing. Characterization of the interactions between H. pylori and the fecal microbiome, as well as the mechanisms underlying these interactions, may offer new therapeutic approaches. Exploration of changes in fatty acid metabolism associated with H. pylori-mediated alterations of the fecal microbiome may also reveal strategies to help prevent progression to neoplasia.
Disciplines
Publication Date
May 25, 2021
DOI
10.1101/2021.05.23.445270
Citation Information
Brian E. White, John D. Sterrett, Zoya Grigoryan, Lauren T. Lally, et al.. "Characterization of gut microbiome and metabolome in Helicobacter pylori patients in an underprivileged community in the United States" bioRxiv (2021)
Available at: http://works.bepress.com/lark-perez/11/
Creative Commons license
Creative Commons License
This work is licensed under a Creative Commons CC_BY International License.