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Acetyl nitrate mediated conversion of methyl ketones to diverse carboxylic acid derivatives.
Organic and Biomolecular Chemistry (2021)
  • Joseph N. Capilato, Rowan University
  • Peter J. Pellegrinelli, Rowan University
  • Josephine Bernard, Rowan University
  • Logan Schnorbus, Rowan University
  • Shane Philippi, Rowan University
  • Joseph Mattiucci, Rowan University
  • Erik P. Hoy, Rowan University
  • Lark J. Perez, Rowan University
Abstract
The development of a novel acetyl nitrate mediated oxidative conversion of methyl ketones to carboxylic acid derivatives is described. By analogy to the haloform reaction and supported by experimental and computational investigation we propose a mechanism for this transformation.

Disciplines
Publication Date
June 23, 2021
DOI
10.1039/D1OB00786F
Citation Information
Joseph N. Capilato, Peter J. Pellegrinelli, Josephine Bernard, Logan Schnorbus, et al.. "Acetyl nitrate mediated conversion of methyl ketones to diverse carboxylic acid derivatives." Organic and Biomolecular Chemistry Vol. 19 Iss. 24 (2021) p. 5298 - 5302
Available at: http://works.bepress.com/lark-perez/10/