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Including walnuts in a low-fat/modified-diet improves HDL cholesterol-to-total cholesterol ratios in patients with Type 2 Diabetes
Faculty of Health and Behavioural Sciences - Papers (Archive)
  • Linda C Tapsell, University of Wollongong
  • Lynda J Gillen
  • Craig S Patch, University of Wollongong
  • Marijka Batterham, University of Wollongong
  • Alice Owen
  • Marian Bare
  • Meredith A Kennedy, University of Wollongong
RIS ID
10891
Publication Date
1-1-2004
Publication Details

Tapsell, L. C., Gillen, L. J., Patch, C. S., Batterham, M., Owen, A., Bare, M. & Kennedy, M. A. (2004). Including walnuts in a low-fat/modified-diet improves HDL cholesterol-to-total cholesterol ratios in patients with Type 2 Diabetes. Diabetes Care, 39078 2777-2783.

Abstract
OBJECTIVE: The aim of this study was to examine the effect of a moderate-fat diet inclusive of walnuts on blood lipid profiles in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS: This was a parallel randomized controlled trial comparing three dietary advice groups each with 30% energy as fat: low fat, modified low fat, and modified low fat inclusive of 30 g of walnuts per day. Fifty-eight men and women, mean age 59.3 +/- 8.1 years, started the trial. Dietary advice was given at baseline with monthly follow-up and fortnightly phone calls for support. Body weight, percent body fat, blood lipids, HbA1c, total antioxidant capacity, and erythrocyte fatty acid levels were measured at 0, 3, and 6 months. Data were assessed by repeated-measures ANOVA with an intention-to-treat model. RESULTS: The walnut group achieved a significantly greater increase in HDL cholesterol-to-total cholesterol ratio (P=0.049) and HDL (P=0.046) than the two other treatment groups. A 10% reduction in LDL cholesterol was also achieved in the walnut group, reflecting a significant effect by group (P=0.032) and time (P=0.036). There were no significant differences between groups for changes in body weight, percent body fat, total antioxidant capacity, or HbA1c levels. The higher dietary polyunsaturated fat-to-saturated fat ratio and intakes of omega-3 fatty acids in the walnut group were confirmed by erythrocyte biomarkers of dietary intake. CONCLUSIONS: Structured "whole of diet" advice that included 30 g of walnuts/day delivering substantial amounts of polyunsaturated fatty acid improved the lipid profile of patients with type 2 diabetes.
Citation Information
Linda C Tapsell, Lynda J Gillen, Craig S Patch, Marijka Batterham, et al.. "Including walnuts in a low-fat/modified-diet improves HDL cholesterol-to-total cholesterol ratios in patients with Type 2 Diabetes" (2004) p. 2777 - 2783
Available at: http://works.bepress.com/l_tapsell/151/