Conversions of Cyclic Amines to Nylon Precursor Lactams Using Bulk Gold and Fumed Silica CatalystsACS Catalysis
Publication VersionPublished Version
AbstractBulk gold powder (∼50 μm) and alumina-supported gold catalyzed the oxidative dehydrogenation of 5-, 6-, and 7-membered cyclic amines to amidines. These amidines were hydrolyzed upon treatment with Aerosil 200 (fumed silica gel) and water, producing lactams in 42–73% yields and amines in 36–63% yields. The gold and Aerosil 200 catalysts could also be combined in a one-pot reaction to catalyze the conversion of cyclic amines to lactams in yields up to 51%.
Copyright OwnerAmerican Chemical Society
Citation InformationErik R. Klobukowski, Mallory L. Mueller, Robert J. Angelici and L. Keith Woo. "Conversions of Cyclic Amines to Nylon Precursor Lactams Using Bulk Gold and Fumed Silica Catalysts" ACS Catalysis Vol. 1 Iss. 7 (2011) p. 703 - 708
Available at: http://works.bepress.com/l-woo/15/