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Heparin vs. saline for peripheral i.v. locks in children
Pediatric nursing
  • Charmaine Kleiber, University of Iowa
  • KIrsten M. Hanrahan, University of Iowa
  • C. L. Fagan
  • M. A. Zittergruen
Document Type
Peer Reviewed
Publication Date
NLM Title Abbreviation
Pediatr Nurs
PubMed ID
PURPOSE: To determine the efficacy of saline versus heparin flush solution to maintain peripheral i.v. locks in a pediatric population. METHOD: A prospective, randomized, double-blind design was used. A sample of 124 peripheral i.vs. were flushed with either saline or heparin in saline. Subjects were infants over 28 days of age and children. FINDINGS: The heparin and saline groups were comparable for total hours duration of the i.v. and for incidence of complications. CONCLUSIONS: Saline is efficacious in maintaining patency of peripheral i.v. locks in children over 28 days of age.
  • Catheterization,
  • Peripheral/nursing,
  • Child,
  • Child,
  • Preschool,
  • Clinical Nursing Research,
  • Double-Blind Method,
  • Heparin/administration & dosage,
  • Humans,
  • Infant,
  • Prospective Studies,
  • Sodium Chloride/administration & dosage,
  • Vascular Patency
Published Article/Book Citation
Pediatric nursing, 19:4 (1993) pp.405-9, 376.
Citation Information
Charmaine Kleiber, KIrsten M. Hanrahan, C. L. Fagan and M. A. Zittergruen. "Heparin vs. saline for peripheral i.v. locks in children" Pediatric nursing Vol. 19 Iss. 4 (1993) p. 405 - 9, 376 ISSN: 0097-9805
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