This study uses general strain theory to examine the direct and indirect relationship between early victimization and drug use. Few previous studies measure strain as victimization. Also, past studies tend to combine drug use measures with delinquency measures. This study expands this research by operationalizing strain as early victimization and using measures of both frequency and onset of drug use. National Survey of Adolescents data is used to test the hypotheses. The results show that when youth are victimized they will use drugs more frequently and use drugs at a younger age. These relationships were only partially mediated by social bonds and negative emotions.