Charity Médecins Sans Frontières (MSF) has called for a radical change in the WHO-recommended tuberculosis control strategy, DOTS (directly observed treatment, short-course). “We are concerned that DOTS is excluding a large number of people with tuberculosis because it is based on sputum microscopy that detects, in the best of circumstances, only about 50% of all those with tuberculosis”, Francine Matthys of MSF complained. “In many places, this proportion is even lower, and with HIV/AIDS, things have got even worse”, she told TLID.