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Application of Poly(amidoamine) Dendrimers for Use in Bionanomotor Systems
MIIR Faculty Research
  • Madhukar Babu Kolli, Marshall University
  • B. Scott Day, Marshall University
  • Hideyo Takatsuki, Marshall University
  • Siva Krishna Nalabotu, Marshall University
  • Kevin M. Rice, Marshall University
  • Kazuhiro Kohama, Marshall University
  • Murali K. Gadde, Marshall University
  • Anjaiah Katta, Marshall University
  • Eric R. Blough, Marshall University
Document Type
Article
Publication Date
5-4-2010
Abstract
The study and utilization of bionanomotors represents a rapid and progressing field of nanobiotechnology. Here, we demonstrate that poly(amidoamine) (PAMAM) dendrimers are capable of supporting heavy meromyosin dependent actin motility of similar quality to that observed using nitrocellulose, and that microcontact printing of PAMAM dendrimers can be exploited to produce tracks of active myosin motors leading to the restricted motion of actin filaments across a patterned surface. These data suggest that the use of dendrimer surfaces will increase the applicability of using protein biomolecular motors for nanotechnological applications.
Comments

Reprinted with permission from Kolli, M. B., Day, B. S., Takatsuki, H., Nalabotu, S. K., Rice, K. M., Kohama, K., ... & Blough, E. R. (2010). Application of poly(amidoamine) dendrimers for use in bionanomotor systems. Langmuir, 26(9), 6079-6082. http://pubs.acs.org/doi/abs/10.1021/la100174h

Copyright 2010 American Chemical Society

Citation Information
Kolli, M. B., Day, B. S., Takatsuki, H., Nalabotu, S. K., Rice, K. M., Kohama, K., ... & Blough, E. R. (2010). Application of poly(amidoamine) dendrimers for use in bionanomotor systems. Langmuir, 26(9), 6079-6082.