SelectedWorks - Kevin M Rice

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Selected Works of Kevin M Rice

Basic Science Division Director, Center for Diagnostic Nanosystems

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About Kevin M Rice

Present	Laboratory Manager, Cell Differentiation and Development Center, Marshall University
Institution Organization Position Type Position Title Time Period to Options Current Position Affiliate my profile with this Institution

Life Sciences, Biotechnology, Laboratory and Basic Science Research, Physiology, Cellular and Molecular Physiology, and Medicine and Health Sciences

phone: 304-696-3267

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Article

Cerium oxide nanoparticle aggregates affect stress response and function in ...

Pharmaceutical Science and Research (2015)

Steven Rogers, Kevin M Rice, Nandini Manne, Tolou Shokuhfar, et al.

Objective: The continual increase in production and disposal of nanomaterials raises concerns regarding the safety of nanoparticles on the environmental ...

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Article

Cerium oxide nanoparticle treatment ameliorates peritonitis-induced diaphragm dysfunction

MIIR Faculty Research (2015)

Shinichi Asano, Ravikumar Arvapalli, Nandini D. Manne, Mani Maheshwari, et al.

The severe inflammation observed during sepsis is thought to cause diaphragm dysfunction, which is associated with poor patient prognosis. Cerium ...

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Article

Lipopolysaccharide induced MAP kinase activation in RAW 264.7 cells ...

Pharmaceutical Science and Research (2015)

Vellaisamy Selvaraj, Niraj Nepa, Steven Rogers, Nandini D.P.K. Manne, et al.

High mortality rates are associated with the life threatening disease of sepsis. Improvements in septic patient survivability have failed to ...

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Article

Inhibition of MAP kinase/NF-kB mediated signaling and attenuation of ...

Pharmaceutical Science and Research (2015)

Vellaisamy Selvaraj, Niraj Nepa, Steven Rogers, Nandini D.P.K. Manne, et al.

Sepsis is a life threatening disease that is associated with high mortality. Existing treatments have failed to improve survivability in ...

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Article

Cerium oxide nanoparticles inhibit lipopolysaccharide inducedMAP kinase/NF-kB mediated severe ...

Pharmaceutical Science and Research (2015)

Mani Maheshwari, Nandini Manne, Shinichi Asano, Eric Blough, et al.

The life threatening disease of sepsis is associated with high mortality. Septic patient survivability with currently available treatments has failed ...

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Article

Differential regulation of apoptosis in slow and fast twitch muscles ...

MIIR Faculty Research (2015)

Kevin M. Rice, Nandini D.P.K. Manne, Murali K. Gadde, Satyanarayana Paturi, et al.

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Article

Cerium oxide nanoparticles attenuate acute kidney injury induced by intra-abdominal ...

Pharmaceutical Science and Research (2015)

Nandini Manne, Ravikumar Arvapalli, Niraj Nepal, Tolou Shokuhfar, et al.

Background Intra-abdominal infection or peritonitis is a cause for great concern due to high mortality rates. The prognosis of severe ...

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Article

Exposure to Cerium Oxide Nanoparticles Is Associated With Activation of ...

Pharmaceutical Science and Research (2015)

Kevin M. Rice, Siva K. Nalabotu, Nandini D.P.K. Manne, Madhukar B. Kolli, et al.

Objectives: With recent advances in nanoparticle manufacturing and applications, potential exposure to nanoparticles in various settings is becoming increasing likely. ...

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Article

Efficacy of Female Rat Models in Translational Cardiovascular Aging Research

Pharmaceutical Science and Research (2014)

Kevin M. Rice, J. C. Fannin, C. Gillette and Eric Blough

Cardiovascular disease is the leading cause of death in women in the United States. Aging is a primary risk factor ...

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Article

Age-associated alterations of cardiac structure and function in the female ...

Pharmaceutical Science and Research (2014)

Jacqueline Fannin, Kevin M. Rice, Srininvas Thulluri, Lucy Dornon, et al.

The Fischer 344/NNiaHSD × Brown Norway/BiNia F1 (F344xBN) rat model exhibits an increased life span and fewer age-associated pathologies compared ...

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Article

Uniaxial stretch-induced regulation of mitogen-activated protein kinase, Akt and p70S6 ...

MIIR Faculty Research (2007)

Kevin M. Rice, Devashish H. Desai, Deborah L. Preston, Paulette S. Wehner, et al.

The effects of ageing on the cardiovascular system contribute to substantial alterations in cellular morphology and function. The variables regulating ...

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Article

Journal of Gerontology: BIOLOGICAL SCIENCES (2006)

Kevin M. Rice, Deborah L. Preston, David Neff, Michael L. Norton, et al.

This study tested the hypothesis that age-related changes in the dystrophin–glycoprotein complex (DGC) may precede age-associated alterations in muscle morphology ...

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Article

Chronic Paracetamol Treatment Influences Indices of Reactive Oxygen Species Accumulation ...

MIIR Faculty Research (2012)

Kevin M. Rice, Sarath Meduru, Sunil K. Kakarla, Anjaiah Katta, et al.

Previous reports have demonstrated that increased levels of reactive oxygen species (ROS) and alterations in cell signaling characterize aging in ...

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Article

Intratracheal Instillation of Cerium Oxide Nanoparticles Induces Hepatic Toxicity in ...

MIIR Faculty Research (2011)

Siva Krishna Nalabotu, Madhukar Babu Kolli, William E. Triest, Jane Y. Ma, et al.

Background: Cerium oxide (CeO2) nanoparticles have been posited to have both beneficial and toxic effects on biological systems. Herein, we ...

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Article

Effect of aging on cellular mechanotransduction

MIIR Faculty Research (2011)

Miaozong Wu, Jacqueline Fannin, Kevin M. Rice, Bin Wang, et al.

Aging is becoming a critical heath care issue and a burgeoning economic burden on society. Mechanotransduction is the ability of ...

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Article

Iron-Induced Cardiac Damage: Role of Apoptosis and Deferasirox Intervention

MIIR Faculty Research (2011)

Yeling Wang, Miaozong Wu, Rabaa M. Al-Rousan, Hua Liu, et al.

Excess cardiac iron levels are associated with cardiac damage and can result in increased morbidity and mortality. Here, we hypothesize ...

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Article

Acetaminophen Improves Protein Translational Signaling in Aged Skeletal Muscle

MIIR Faculty Research (2010)

Miaozong Wu, Hua Liu, Jacqueline Fannin, Anjaiah Katta, et al.

Background: Age-related muscle atrophy is characterized by increased oxidative stress, diminished Akt enzymatic function, and reduced phosphorylation of the mammalian ...

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Article

Application of Poly(amidoamine) Dendrimers for Use in Bionanomotor Systems

MIIR Faculty Research (2010)

Madhukar Babu Kolli, B. Scott Day, Hideyo Takatsuki, Siva Krishna Nalabotu, et al.

The study and utilization of bionanomotors represents a rapid and progressing field of nanobiotechnology. Here, we demonstrate that poly(amidoamine) (PAMAM) ...

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Article

Possible Molecular Mechanisms Underlying Age-Related Cardiomyocyte Apoptosis in the F344XBN ...

Biological Sciences Faculty Research (2010)

Sunil K. Kakarla, Kevin M. Rice, Anjaiah Katta, Satyanarayana Paturi, et al.

Despite advances in treatment, age-related cardiac dysfunction still remains a leading cause of cardiovascular death. Recent data have suggested that ...

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Article

Fluprostenol-Induced MAPK Signaling is Independent of Aging in Fischer 344 ...

MIIR Faculty Research (2010)

Kevin M. Rice, Ernest M. Walker, Sunil K. Kakarla, Satyanarayana Paturi, et al.

The factors that regulate vascular mechanotransduction and how this process may be altered with aging are poorly understood and have ...

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Article

Altered Regulation of Contraction-Induced Akt/mTOR/p70S6k Pathway Signaling in ...

MIIR Faculty Research (2009)

Anjaiah Katta, Sunil K. Kakarla, Miaozong Wu, Satyanarayana Paturi, et al.

Increased muscle loading results in the phosphorylation of the 70 kDa ribosomal S6 kinase (p70S6k), and this event is strongly ...

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Article

Acetaminophen Combinations Protect Against Iron-Induced Cardiac Damage in Gerbils

MIIR Faculty Research (2009)

Ernest M. Walker, Ryan G. Morrison, Lucy Dornon, Joseph P. Laurino, et al.

This study tested if acetaminophen, N-methyl-D-glucamine dithiocarbamate (NMGDTC), deferoxamine, and combinations of these agents reduce excess iron content, prevent iron-induced ...

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Article

Aging-Associated Dysfunction of Akt/Protein Kinase B: S-Nitrosylation and Acetaminophen ...

MIIR Faculty Research (2009)

Miaozong Wu, Anjaiah Katta, Murali K. Gadde, Hua Liu, et al.

Background: Aged skeletal muscle is characterized by an increased incidence of metabolic and functional disorders, which if allowed to proceed ...

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Article

Lean and obese Zucker rats exhibit different patterns of p70s6 ...

MIIR Faculty Research (2009)

Anjaiah Katta, Sunil K. Karkala, Miaozong Wu, Sarath Meduru, et al.

Increased phosphorylation of the 70-kDa ribosomal S6 kinase (p70S6k) signaling is strongly correlated with the degree of muscle adaptation following ...

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Article

Acetaminophen prevents aging-associated hyperglycemia in aged rats: effect of aging-associated ...

MIIR Faculty Research (2009)

Miaozong Wu, Devashish H. Desai, Sunil K. Kakarla, Anjaiah Katta, et al.

Background Aging-related hyperglycemia is associated with increased oxidative stress and diminished muscle glucose transporter-4 (Glut4) that may be regulated, at ...

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About Kevin M Rice

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