Early intervention around mental health and wellness is a vital piece for the school system to address when working holistically with students. The American School Counselor Association (ASCA) and the Substance Abuse and Mental Health Services Administration (SAMHSA) emphasize the importance for schools to develop a comprehensive systemic framework around the academic, social, and emotional needs of students. By using the Multi-tiered System of Supports (MTSS), school districts can administer Universal Mental Health Screening (UMHS), a Tier 1 intervention, to help identify students who may be considered at risk for mental health and wellness issues. Unfortunately, less than 15% of K–12 schools in the United States engage in UMHS with their students. For one specialized population, gifted and talented students, specifically ones attending an accelerative, residential program, there is minimal published data regarding their mental health, wellness, and intervention-based supports. Also, none of the publicly-funded schools for these students in the United States have a UMHS process for their student population. This quantitative study aimed to institute a Tier 1 UMHS process for gifted and talented students attending an accelerative, residential program to evaluate mental health and resiliency factors. The researcher used the Beck Youth Inventories--2nd edition (BYI-2) and the Resiliency Scales for Children and Adolescents (RSCA) to assess prevalent concerns, identified strengths, and potential correlation between screening factors and gifted and talented students who are at risk.