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Screening and Treatment Outcomes in Adults and Children With Type 1 Diabetes and Asymptomatic Celiac Disease: The CD-DIET Study.
Diabetes care
  • Farid H Mahmud
  • Antoine B M Clarke
  • Kariym C Joachim
  • Esther Assor
  • Charlotte McDonald
  • Fred Saibil
  • Heather A Lochnan
  • Zubin Punthakee
  • Amish Parikh
  • Andrew Advani
  • Baiju R Shah
  • Bruce A Perkins
  • Caroline S Zuijdwijk
  • David R Mack
  • Dror Koltin
  • Emilia N De Melo
  • Eugene Hsieh
  • Geetha Mukerji
  • Jeremy Gilbert
  • Kevin Bax, Pediatric Gastroenterology, Department of Pediatrics, Children’s Hospital, London Health Sciences Centre, Western University, London, Ontario, Canada
  • Margaret L Lawson
  • Maria Cino
  • Melanie D Beaton
  • Navaaz A Saloojee
  • Olivia Lou
  • Patricia H Gallego
  • Premysl Bercik
  • Robyn L Houlden
  • Ronnie Aronson
  • Susan E Kirsch
  • William G Paterson
  • Margaret A Marcon
Document Type
Article
Publication Date
7-1-2020
URL with Digital Object Identifier
https://doi.org/10.2337/dc19-1944
Disciplines
Abstract

OBJECTIVE: To describe celiac disease (CD) screening rates and glycemic outcomes of a gluten-free diet (GFD) in patients with type 1 diabetes who are asymptomatic for CD.

RESEARCH DESIGN AND METHODS: Asymptomatic patients (8-45 years) were screened for CD. Biopsy-confirmed CD participants were randomized to GFD or gluten-containing diet (GCD) to assess changes in HbA

RESULTS: Adults had higher CD-seropositivity rates than children (6.8% [95% CI 4.9-8.2%,

CONCLUSIONS: CD is frequently observed in asymptomatic patients with type 1 diabetes, and clinical vigilance is warranted with initiation of a GFD.

Creative Commons License
Creative Commons Attribution-Noncommercial-No Derivative Works 4.0
Citation Information
Farid H Mahmud, Antoine B M Clarke, Kariym C Joachim, Esther Assor, et al.. "Screening and Treatment Outcomes in Adults and Children With Type 1 Diabetes and Asymptomatic Celiac Disease: The CD-DIET Study." Diabetes care Vol. 43 Iss. 7 (2020) p. 1553 - 1556
Available at: http://works.bepress.com/kevin-bax/3/