Reversible Inactivation and Desiccation Tolerance of Silicified VirusesJournal of Virology
SponsorThis work was supported by Portland State University, the NASA Astrobiology Institute's Director's Discretionary Fund (grant number NNA11AC01G), and a National Science Foundation Integrative Graduate Education and Research Traineeship (NSF-IGERT) fellowship (to J.R.L.)
- Bacteriophage T4 -- Dispersal,
- Molecular virology,
AbstractLong-distance host-independent virus dispersal is poorly understood, especially for viruses found in isolated ecosystems. Todemonstrate a possible dispersal mechanism, we show that bacteriophage T4, archaeal virus Sulfolobus spindle-shaped virus Kamchatka, and vaccinia virus are reversibly inactivated by mineralization in silica under conditions similar to volcanic hotsprings. In contrast, bacteriophage PRD1 is not silicified. Moreover, silicification provides viruses with remarkable desiccationresistance, which could allow extensive aerial dispersal.
Citation InformationLaidler, J. R., Shugart, J. A., Cady, S. L., Bahjat, K. S., & Stedman, K. M. (2013). Reversible Inactivation and Desiccation Tolerance of Silicified Viruses. Journal of virology, 87(24), 13927-13929.