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Reversible Inactivation and Desiccation Tolerance of Silicified Viruses
Journal of Virology
  • James R. Laidler, Portland State University
  • Jessica A. Shugart, Earle A. Chiles Research Institute
  • Sherry L. Cady, Portland State University
  • Keith S. Bahjat, Earle A. Chiles Research Institute
  • Kenneth M. Stedman, Portland State University
Document Type
Publication Date
  • Bacteriophages,
  • Bacteriophage T4 -- Dispersal,
  • Molecular virology,
  • Vaccinia

Long-distance host-independent virus dispersal is poorly understood, especially for viruses found in isolated ecosystems. To
demonstrate a possible dispersal mechanism, we show that bacteriophage T4, archaeal virus Sulfolobus spindle-shaped virus Kamchatka, and vaccinia virus are reversibly inactivated by mineralization in silica under conditions similar to volcanic hot
springs. In contrast, bacteriophage PRD1 is not silicified. Moreover, silicification provides viruses with remarkable desiccation
resistance, which could allow extensive aerial dispersal.


Copyright 2013, American Society for Microbiology. This is the publisher's final PDF reproduced here with author and publisher permission. The original instance can be found at:

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Citation Information
Laidler, J. R., Shugart, J. A., Cady, S. L., Bahjat, K. S., & Stedman, K. M. (2013). Reversible Inactivation and Desiccation Tolerance of Silicified Viruses. Journal of virology, 87(24), 13927-13929.