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Healthy dietary patterns and risk of mortality and ESRD in CKD: A meta-analysis of cohort studies
Clinical Journal of the American Society of Nephrology
  • Jaimon T Kelly, Bond University
  • Suetonia C Palmer, University of Otago Christchurch
  • Shu Ning Wai, Bond University
  • Marinella Ruospo, University of Eastern Piedmont Amedeo Avogadro
  • Juan-Jesus Carrero, Karolinska Institutet
  • Katrina Campbell, Bond University
  • Giovanni F M Strippoli, University of Bari; University of Sydney
Date of this Version
12-8-2016
Document Type
Journal Article
Publication Details

Citation only

Kelly, J. T., Palmer, S. C., Wai, S. N., Ruospo, M., Carrero, J. J., Campbell, K. L., & Strippoli, G. F. (2016, in press). Healthy dietary patterns and risk of mortality and ESRD in CKD: A meta-analysis of cohort studies. Clinical Journal of the American Society of Nephrology.

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Copyright © 2016 by the American Society of Nephrology

Abstract
BACKGROUND AND OBJECTIVES: Patients with CKD are advised to follow dietary recommendations that restrict individual nutrients. Emerging evidence indicates overall eating patterns may better predict clinical outcomes, however, current data on dietary patterns in kidney disease are limited. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: This systematic review aimed to evaluate the association between dietary patterns and mortality or ESRD among adults with CKD. Medline, Embase, and reference lists were systematically searched up to November 24, 2015 by two independent review authors. Eligible studies were longitudinal cohort studies reporting the association of dietary patterns with mortality, cardiovascular events, or ESRD. RESULTS: A total of seven studies involving 15,285 participants were included. Healthy dietary patterns were generally higher in fruit and vegetables, fish, legumes, cereals, whole grains, and fiber, and lower in red meat, salt, and refined sugars. In six studies, healthy dietary patterns were consistently associated with lower mortality (3983 events; adjusted relative risk, 0.73; 95% confidence interval, 0.63 to 0.83; risk difference of 46 fewer (29-63 fewer) events per 1000 people over 5 years). There was no statistically significant association between healthy dietary patterns and risk of ESRD (1027 events; adjusted relative risk, 1.04; 95% confidence interval, 0.68 to 1.40). CONCLUSIONS: Healthy dietary patterns are associated with lower mortality in people with kidney disease. Interventions to support adherence to increased fruit and vegetable, fish, legume, whole grain, and fiber intake, and reduced red meat, sodium, and refined sugar intake could be effective tools to lower mortality in people with kidney disease.
Citation Information
Jaimon T Kelly, Suetonia C Palmer, Shu Ning Wai, Marinella Ruospo, et al.. "Healthy dietary patterns and risk of mortality and ESRD in CKD: A meta-analysis of cohort studies" Clinical Journal of the American Society of Nephrology (2016) ISSN: 1555-905X
Available at: http://works.bepress.com/katrina-campbell/21/