Article
Chromosome Dynamics: New Light on Aurora B Kinase Function
Current Biology
Abstract
Aurora B family kinases play an essential role in chromosome segregation and cytokinesis. Recent work suggests that the kinase activity is required for bipolar chromosome orientation, kinetochore assembly, spindle checkpoint and microtubule dynamics. Aurora B also has additional functions in chromosome condensation and cohesion.
Department(s)
Biological Sciences
Keywords and Phrases
- Caenorhabditis elegans Proteins,
- Chromosomal Proteins, Non-Histone,
- Chromosome Segregation,
- Chromosomes,
- Dynein ATPase,
- Protein Kinases,
- Protein-Serine-Threonine Kinases,
- Animals,
- Autoantigens,
- Humans,
- Kinetochores,
- Microtubules,
- Mitosis,
- Saccharomyces cerevisiae Proteins,
- AURKA Protein, Human,
- AURKB Protein, Human,
- Aurkb Protein, Mouse,
- Aurora Kinase,
- Centromere Protein A,
- Centromere Protein E,
- Dynein Adenosine Triphosphatase,
- IPL1 Protein, S cerevisiae,
- Nonhistone Protein,
- Protein Kinase,
- Centromere,
- Genetics,
- Human,
- Metabolism,
- Mitosis,
- Note,
- Physiology
Document Type
Article - Journal
Document Version
Citation
File Type
text
Language(s)
English
Rights
© 2002 Cell Press, All rights reserved.
Publication Date
7-1-2002
Publication Date
01 Jul 2002
PubMed ID
12121637
Disciplines
Citation Information
Katie Shannon and Edward D. Salmon. "Chromosome Dynamics: New Light on Aurora B Kinase Function" Current Biology Vol. 12 Iss. 13 (2002) p. R458 - R460 ISSN: 0960-9822;1879-0445 Available at: http://works.bepress.com/katie_shannon/16/