The manuscript's importance is enhanced by the presence of a non-scribal colophon of the year 1375 which indicates its exact location at this date. The present analysis will be concerned first with securing Vat. gr. 352's position as the fourth Lectionary manuscript of the first group through a comparative study of its ornamental headpieces, illuminated initials, and script style. The second half of the paper will examine several entries in the Menologium texts of the Lectionary manuscripts and conclude with a brief consideration of the historical circumstances and implications of Vat. gr. 352's colophon.