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Faculty Selected Works of Kamila White
Article
Perceived Health Mediates Effects of Physical Activity on Quality of Life in Patients With a Fontan Circulation
American Journal of Cardiology (2019)
  • Christina E. Holbein, Children's Hospital of Philadelphia
  • Gruschen R. Veldtman, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
  • Philip Moons, Katholieke Universiteit Leuven
  • Philip Moons, University of Cape Town
  • Philip Moons, University of Gothenburg
  • Adrienne H. Kovacs, Peter Munk Cardiac Centre, University Health Network, University of Toronto, Toronto, Canada
  • Koen Luyckx, School Psychology and Development in Context, KU Leuven - University of Leuven, Leuven, Belgium
  • Silke Apers, Katholieke Universiteit Leuven
  • Shanti Chidambarathanu, National Heart Foundation of Australia
  • Alexandra Soufi, Department of Congenital Heart Disease, Louis Pradel Hospital, Hospices civils de Lyon, Lyon, France
  • Katrine Eriksen, Oslo University Hospital
  • Jamie L. Jackson, Nationwide Children's Hospital
  • Junko Enomoto, Department of Adult Congenital Heart Disease, Chiba Cardiovascular Center, Chiba, Japan
  • Susan M. Fernandes, Stanford University
  • Bengt Johansson, Umeå University
  • Luis Alday, Division of Cardiology, Hospital de Niños, Córdoba, Argentina
  • Mikael Dellborg, Adult Congenital Heart Unit, Sahlgrenska University Hospital/Östra, Gothenburg, Sweden
  • Malin Berghammer, University College West
  • Malin Berghammer, University of Gothenburg
  • Samuel Menahem, Monash University
  • Maryanne Caruana, Mater Dei Hospital
  • Shelby Kutty, University of Nebraska Medical Center
  • Andrew S. Mackie, University of Alberta
  • Corina Thomet, University of Bern
  • Werner Budts, Katholieke Universiteit Leuven
  • Kamila White, University of Missouri–St. Louis
  • Maayke A. Sluman, Department of Cardiology, Academic Medical Center, Amsterdam, the Netherlands
  • Edward Callus, Clinical Psychology Service, IRCCS Policlinico San Donato, Milan, Italy
  • Stephen C. Cook, Boston Children's Hospital
  • Paul Khairy, Montreal Heart Institute
  • Ari Cedars, University of Texas Southwestern Medical Center
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Abstract
Patients with a Fontan circulation are at risk of a sedentary lifestyle. Given the direct relationship between physical activity and health, promotion of physical activity has the potential to improve outcomes, including quality of life (QOL). This study aimed to describe self-reported physical activity levels in adult Fontan patients and examine associations between physical activity, perceived health status and QOL. The sample consisted of 177 Fontan patients (Mage = 27.5 ± 7.6 years, 52% male) who reported their physical activity, perceived health status, and QOL as part of the cross-sectional Assessment of Patterns of Patient-Reported Outcomes in Adults with Congenital Heart disease - International Study. Descriptive statistics and univariate analyses of variance with planned contrasts were computed to describe physical activity characteristics. Mediation analyses tested whether perceived health status variables mediated the association between physical activity and QOL. Forty-six percent of patients were sedentary while only 40% met international physical activity guidelines. Higher physical activity was associated with younger age, lower NYHA class, higher perceived general health, and greater QOL. Patients who commuted by walking and engaged in sports reported better perceived health and QOL. Mediation analyses revealed that perceived general health but not NYHA functional class mediated the association between physical activity and QOL (αβ = 0.22, 95% confidence interval = 0.04 to 0.49). In conclusion, Fontan patients likely benefit from regular physical activity, having both higher perceived general health and functional capacity; greater perceived health status may contribute to enhanced QOL. In conclusion, these data support the pivotal role of regular physical activity for Fontan patients.
Keywords
  • quality of life,
  • fontan circulation,
  • physical activity
Disciplines
Publication Date
July 1, 2019
DOI
10.1016/J.AMJCARD.2019.03.039
Citation Information
Christina E. Holbein, Gruschen R. Veldtman, Philip Moons, Philip Moons, et al.. "Perceived Health Mediates Effects of Physical Activity on Quality of Life in Patients With a Fontan Circulation" American Journal of Cardiology Vol. 124 Iss. 1 (2019) p. 144 - 150
Available at: http://works.bepress.com/kamila-white/74/