Article
Core-shell Hydrogel Microcapsules for Improved Islets Encapsulation
Advanced Healthcare Materials
Document Type
Article
Disciplines
Publication Version
Accepted Manuscript
Publication Date
1-1-2013
DOI
10.1002/adhm.201200341
Abstract
Islets microencapsulation holds great promise to treat type 1 diabetes. Currently used alginate microcapsules often have islets protruding outside capsules, leading to inadequate immuno-protection. A novel design of microcapsules with core–shell structures using a two-fluid co-axial electro-jetting is reported. Improved encapsulation and diabetes correction is achieved in a single step by simply confining the islets in the core region of the capsules.
Copyright Owner
WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Copyright Date
2013
Language
en
File Format
application/pdf
Citation Information
Minglin Ma, Kaitlin M. Bratlie and et al.. "Core-shell Hydrogel Microcapsules for Improved Islets Encapsulation" Advanced Healthcare Materials Vol. 2 Iss. 5 (2013) p. 667 - 672 Available at: http://works.bepress.com/kaitlin_bratlie/20/
This is the peer reviewed version of the following article: Ma, M., Chiu, A., Sahay, G., Doloff, J. C., Dholakia, N., Thakrar, R., Cohen, J., Vegas, A., Chen, D., Bratlie, K. M., Dang, T., York, R. L., Hollister-Lock, J., Weir, G. C. and Anderson, D. G. (2013), Core–Shell Hydrogel Microcapsules for Improved Islets Encapsulation. Advanced Healthcare Materials, 2: 667–672, which has been published in final form at doi:10.1002/adhm.201200341. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. Posted with permission.