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Article
Aqueous Red-Emitting Silicon Nanoparticles for Cellular Imaging: Consequences of Protecting Against Surface Passivation by Hydroxide and Water for Stable Red Emission
Journal of Materials Research
  • Sheng-Kuei Chiu, Portland State University
  • Beth Ann Manhat, Portland State University
  • William J.I. DeBenedetti, Portland State University
  • Anna L. Brown, Portland State University
  • Katye Fichter, Oregon Health & Science University
  • Tania Vu, Oregon Health & Science University
  • Micah Eastman, Portland State University
  • Jun Jiao, Portland State University
  • Andrea Mitchell Goforth, Portland State University
Document Type
Article
Publication Date
1-1-2013
Subjects
  • Semiconductor nanoparticles,
  • Nanosilicon,
  • Aqueous chemistry
Disciplines
Abstract
Stable, aqueous, red-to-near infrared emission is critical for the use of silicon nanoparticles (Si NPs) in biological fluorescence assays, but such Si NPs have been difficult to attain. We report a synthesis and surface modification strategy that protects Si NPs and preserves red photoluminescence (PL) in water for more than 6 mo. The Si NPs were synthesized via high temperature reaction, liberated from an oxide matrix, and functionalized via hydrosilylation to yield hydrophobic particles. The hydrophobic Si NPs were phase transferred to water using the surfactant cetyltrimethylammonium bromide (CTAB) with retention of red PL. CTAB apparently serves a double role in providing stable, aqueous, red-emitting Si NPs by (i) forming a hydrophobic barrier between the Si NPs and water and (ii) providing aqueous colloidal stability via the polar head group. We demonstrate preservation of the aqueous red emission of these Si NPs in biological media and examine the effects of pH on emission color.
Description

This is the publisher's final PDF. Article appears in Journal of Materials Research (http://www.mrs.org/jmr/) and is copyrighted 2013 by Materials Research Society. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the Materials Research Society.

DOI
10.1557/jmr.2012.377
Persistent Identifier
http://archives.pdx.edu/ds/psu/10391
Citation Information
Sheng-Kuei Chiu, Beth A. Manhat, William J.I. DeBenedetti, Anna L. Brown, Katye Fichter, Tania Vu, Micah Eastman, Jun Jiao and Andrea M. Goforth (2013). Aqueous red-emitting silicon nanoparticles for cellular imaging: Consequences of protecting against surface passivation by hydroxide and water for stable red emission. Journal of Materials Research, 28, pp 216-230. doi:10.1557/jmr.2012.377.