The United States is entering a new era, a period marked by some important demographic changes in the composition of the population, most especially significant increases in the Latino and Latino immigrant segments of society. These population shifts require corresponding interpersonal, organizational, and structural changes. The present issue bridges research and theory across disciplines and includes studies incorporating a variety of methodologies to examine these important areas. These articles begin to fill some of the voids where a systematic and robust corpus of knowledge is lacking. The contributions address topics ranging from issues of identity and interpersonal relations to pressing matters of educational significance to general approaches to navigating the cultural transitions that mark fluid transnational adaptations. Finally, each contribution delineates the policy implications resulting from the processes and literatures that are examined.