© 2015 Hanley & Belfus. Study design: Clinical measurements. Purpose: Perform the translation and cross-cultural adaptation of the Patient Rated Wrist Evaluation (PRWE) into a Brazilian version (PRWE-BR), and assess its internal consistency, test-retest reliability and construct validity. Methods: PRWE-BR was developed using standardized guidelines. Sixty-one patients with different wrist injuries were recruited. They were submitted to two assessments, 2-7 days apart. Reliability was measured by internal consistency (Cronbach's alpha) and test-retest reliability (Intraclass Correlation Coefficient). Construct validity was determined via hypothesis testing (Spearman's correlation) of correlations with subscales of SF-36 and DASH. Results: PRWE-BR and its subscales achieved high internal consistency (Cronbach's alpha ≥ 0.85) and excellent test-retest reliability (ICC ≥ 0.90). Construct validity was established by confirmation of 85.7% of our previously formulated hypotheses. Conclusions: PRWE-BR is a valid and reliable tool for the assessment of pain and dysfunction in Brazilian patients with injuries involving the wrist joint. Level of evidence N/A