© 2015 by Begell House, Inc. Stroke is one of the leading causes of disability. Physical rehabilitation must be evidence-based and address a range of clinical subtypes and severity of disabilities. Clinical practice guidelines provide a useful mechanism for implementing rehabilitation plans based on research evidence. To increase adherence to guideline use, there is a need to understand attitudes and intentions toward guideline implementation. The purpose of this paper is to dem-onstrate how theory can be applied to understand therapists’ intention toward implementation of rehabilitation clinical practice guidelines to provide a mechanism for improving use of stroke guidelines in practice.