Following a rise in university-industry relationships (UIRs), scholars began questioning the efficacy of those relationships, as well as whether industry and university research interests and integrity are being compromised. Although many of these studies focus on the university, few examine the perspectives of industry participants. We conducted intensive interviews with 63 managers and scientists at agricultural biotechnology companies involved in UIRs related to agricultural biotechnology. Our analysis of their comments reveals nuanced critical perspectives of UIRs and creative ideas for reforming policies and practices. Industry representatives listed many advantages of UIRs, but some also expressed an interest in reforming policies to preserve a public-interest emphasis for university research. We conclude by considering the structural relationships that may explain the industry representatives' critical evaluations and by identifying policy implications.