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Article
Astrovirus Infection in Hatchling Turkeys: Histologic, Morphometric, and Ultrastructural Findings
Avian Diseases
  • Mari L. Thouvenelle, Iowa State University
  • Joseph S. Haynes, Iowa State University
  • Don L. Reynolds, Iowa State University
Document Type
Article
Publication Version
Published Version
Publication Date
1-1-1995
DOI
10.2307/1591875
Abstract
In three separate experiments, 2- or 5-day-old commercial turkey poults were inoculated orally with astrovirus and examined for clinical signs and for gross and microscopic lesions over a period of 14 days. By day 2 postinoculation (PI), inoculated poults had de- veloped diarrhea, generalized loss of intestinal tone, and dilated ceca that contained light- yellow fluid feces and gas; these changes persisted through day 10 PI. Mild crypt hyperplasia was the only change discernible by light microscopy, and it was first noted in the proximal jejunum on day 1 PI, in the distal jejunum and ileum on day 3 PI, and in the duodenum on day 5 PI. A significant (P < 0.05) increase in crypt depth and area was documented by image analysis on day 3 PI. Ultrastructural evaluation revealed intracytoplasmic aggregates of astro- virus in enterocytes on the sides and base of villi in the ileum and distal jejunum on day 3 PI. Based on the findings, it was concluded that astrovirus caused lesions and replicated in both upper and lower segments of the small intestine in turkey poults.
Comments

This article is published as Thouvenelle, Mari L., Joseph S. Haynes, and Don L. Reynolds. "Astrovirus infection in hatchling turkeys: histologic, morphometric, and ultrastructural findings." Avian diseases (1995): 328-336. doi: 10.2307/1591875. Posted with permission.

Copyright Owner
American Association of Avian Pathologists
Language
en
File Format
application/pdf
Citation Information
Mari L. Thouvenelle, Joseph S. Haynes and Don L. Reynolds. "Astrovirus Infection in Hatchling Turkeys: Histologic, Morphometric, and Ultrastructural Findings" Avian Diseases Vol. 39 Iss. 2 (1995) p. 328 - 336
Available at: http://works.bepress.com/joseph-haynes/10/