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Article
Patient delay and receipt of thrombolytic therapy among patients with acute myocardial infarction from a community-wide perspective
Quantitative Health Sciences Publications and Presentations
  • Robert J. Goldberg, University of Massachusetts Medical School
  • Jerry H. Gurwitz, University of Massachusetts Medical School
  • Jorge L. Yarzebski, University of Massachusetts Medical School
  • J. Landon
  • Joel M. Gore, University of Massachusetts Medical School
  • Joseph S. Alpert, University of Massachusetts Medical School
  • P. M. Dalen
  • James E. Dalen
UMMS Affiliation
Department of Medicine, Division of Cardiovascular Medicine
Date
8-15-1992
Document Type
Article
Medical Subject Headings
Adolescent; Adult; Aged; Aged, 80 and over; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Myocardial Infarction; Patient Acceptance of Health Care; Thrombolytic Therapy; Time Factors
Abstract

The duration of patient delay from the time of onset of symptoms of acute myocardial infarction (AMI) to hospital presentation, and the relation of delay time and various patient characteristics to receipt of thrombolytic therapy were examined as part of a community-based study of patients hospitalized with AMI in the Worcester, Massachusetts, metropolitan area. In all, 800 patients with validated AMI hospitalized at 16 hospitals in the Worcester metropolitan area in 1986 and 1988 constituted the study sample. Patients delayed on average 4 hours between noting symptoms suggestive of AMI and presenting to area-wide emergency departments with no significant change observed between 1986 and 1988. The shorter the time interval of delay, the greater the likelihood of receiving thrombolytic therapy; patients arriving at the emergency department within 1 hour of the onset of acute symptoms were approximately 2.5 and 6.5 times more likely to receive thrombolytic agents than were those presenting to the hospital between 4 and 6, and greater than 6 hours, respectively, after the onset of symptoms. Results of a multivariate analysis showed increasing length of delay, older age, history of hypertension or AMI and non-Q-wave AMI to be significantly associated with failure to receive thrombolytic therapy.

Rights and Permissions
Citation: Am J Cardiol. 1992 Aug 15;70(4):421-5.
Related Resources
Link to Article in PubMed
Citation Information
Robert J. Goldberg, Jerry H. Gurwitz, Jorge L. Yarzebski, J. Landon, et al.. "Patient delay and receipt of thrombolytic therapy among patients with acute myocardial infarction from a community-wide perspective" Vol. 70 Iss. 4 (1992) ISSN: 0002-9149 (Linking)
Available at: http://works.bepress.com/jorge_yarzebski/42/