Skip to main content
Article
Electrochemical glutamate biosensing with nanocube and nanosphere augmented single-walled carbon nanotube networks: a comparative study
Journal of Materials Chemistry
  • Jonathan C. Claussen, Purdue University - Main Campus
  • Mayra S. Artiles, Purdue University
  • Eric S. McLamore, Purdue University
  • Subhashree Mohanty, Purdue University
  • Jin Shi, Purdue University
  • Jenna Rickus, Purdue University - Main Campus
  • Timothy S. Fisher, Purdue University
  • D. Marshall Porterfield, Purdue University - Main Campus
Abstract

We describe two hybrid nanomaterial biosensor platforms, based on networks of single-walled carbon nanotubes (SWCNTs) enhanced with Pd nanocubes and Pt nanospheres and grown in situ from a porous anodic alumina (PAA) template. These nanocube and nanosphere SWCNT networks are converted into glutamate biosensors by immobilizing the enzyme glutamate oxidase (cross-linked with gluteraldehyde) onto the electrode surface. The Pt nanosphere/SWCNT biosensor outperformed the Pd nanocube/SWCNT biosensor and previously reported similar nanomaterial-based biosensors by amperometrically monitoring glutamate concentrations with a wide linear sensing range (50 nM to 1.6 mM) and a small detection limit (4.6 nM, 3 sigma). These results combined with the biosensor fabrication scheme (in situ growth of SWCNTs, electrodeposition of metal nanoparticles, and facile enzyme immobilization protocol) create a biosensor that can potentially be scaled for integration into a wide range of applications including the treatment of neurological disorders.

Keywords
  • NANOELECTRODE ARRAYS; GLUCOSE BIOSENSORS; COLLOIDAL SOLUTION; GLASSY-CARBON; NANOPARTICLES; PLATINUM; ELECTRODES; BIOFUNCTIONALIZATION; ELECTROCATALYSTS; FABRICATION
Date of this Version
1-1-2011
DOI
10.1039/c1jm11561h
Citation
J. Mater. Chem., 2011,21, 11224-11231
Citation Information
Jonathan C. Claussen, Mayra S. Artiles, Eric S. McLamore, Subhashree Mohanty, et al.. "Electrochemical glutamate biosensing with nanocube and nanosphere augmented single-walled carbon nanotube networks: a comparative study" Journal of Materials Chemistry (2011)
Available at: http://works.bepress.com/jonathan_claussen/11/