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Article
Photoinduced Reduction of PtIV within an Anti-Proliferative PtIV–Texaphyrin Conjugate
Chemistry - A European Journal (2014)
  • Grégory Thiabaud, The University of Texas at Austin
  • Jonathan Arambula, The University of Texas at Austin
  • Zahid H. Siddik, The University of Texas M. D. Anderson Cancer Center
  • Jonathan L. Sessler, The University of Texas at Austin
Abstract
Invited for the cover of this issue are the groups of Jonathan Sessler at The University of Texas at Austin and Zahid Siddik at The University of Texas M.D. Anderson Cancer Center in Houston, Texas. The cover picture depicts a tumor-targeting texaphyrin platinum(IV) conjugate that undergoes controlled reduction and subsequent release of the platinum moiety that can then bind DNA. This conjugate is found to inhibit cell proliferation in ovarian cancer cell lines.
Keywords
  • Chemistry,
  • Photoinduced reduction,
  • Physical Sciences
Disciplines
Publication Date
July 14, 2014
DOI
10.1002/chem.201403559
Citation Information
Grégory Thiabaud, Jonathan Arambula, Zahid H. Siddik and Jonathan L. Sessler. "Photoinduced Reduction of PtIV within an Anti-Proliferative PtIV–Texaphyrin Conjugate" Chemistry - A European Journal Vol. 20 Iss. 29 (2014) p. 8813
Available at: http://works.bepress.com/jonathan-arambula/3/