Sixty-two species of caddisflies (Trichoptera) were identified from collections make from Wildcat Creek over a period of 33 years. A new distributional record for South Carolina was obtained for Diplectrona metaqui. Eight species, Polycentropus carlsoni, Wormaldia thyria, Neotrichia collata, Stactobiella delira, Neophylax atlanta, Goera fuscula, Pseudogoera singularis, and Agarodes griseus, are considered to be threatened in South Carolina.