Skip to main content
A Solvent-Free Oxidation of Alcohols in an Organic Laboratory
Journal of Chemical Education (2003)
  • John J. Esteb, Butler University
  • Michael W. Schelle
  • Anne M. Wilson

An oxidation experiment for a first-year organic chemistry class is presented. This oxidation utilizes a solid mixture of CuSO4•5H2O and KMnO4 prepared by mortar and pestle. The oxidations take place under solvent-free conditions and near quantitative yields are obtained for the reactions. Thin-layer chromatography is used to monitor the progress of the reaction. This experiment provides for the simple oxidation of a secondary alcohol to a ketone using a relatively nontoxic oxidizing agent under solvent-free conditions.

Note:Link is to the article in a subscription database available to users affiliated with Butler University. Appropriate login information will be required for access. Users not affiliated with Butler University should contact their local librarian for assistance in locating a copy of this article.

Publication Date
Citation Information
John J. Esteb, Michael W. Schelle and Anne M. Wilson. "A Solvent-Free Oxidation of Alcohols in an Organic Laboratory" Journal of Chemical Education Vol. 80 Iss. 8 (2003)
Available at: