Missouri Bridge P0058 was selected from a list of structurally deficient bridges for strengthening of its main carrying members. This paper presents the strengthening systems employed to increase the flexural and shear capacity of the main carrying members, and the results of the pre-strengthening load test. The load test was conducted to compare the analytical and experimental load rating of the bridge before the strengthening of the bridge was executed. The strengthening systems included (1) CFRP; (2) carbon fiber reinforced cementitious material (CFRCM); (3) polyparaphenylene benzobisoxazole (PBO) using FRCM; and (4) Steel Reinforced Grout (SRG). Bridge P0058 is the first field application in the world employing CFRCM, PBO-FRCM and SRG to increase the flexural and shear carrying capacity of an existing reinforced concrete bridge superstructure. In the following sections, a brief summary of the procedures utilized in the pre-strengthening load testing, design, and installation of the different strengthening systems is introduced.