Skip to main content
Article
Influence of prednisolone on urinary calcium oxalate and struvite relative supersaturation in healthy young adult female domestic shorthaired cats
Veterinary Therapeutics (2007)
  • N Geyer
  • Joe Bartges, University of Tennessee - Knoxville
  • C A Kirk
  • S Cox
  • A Hezel
  • T Moyers
  • J Hayes
Abstract

Prednisolone (10 mg PO q24h) or placebo was administered to healthy cats for 2 weeks in a masked, placebo-controlled, crossover-design study, and 24-hour urine samples were collected. When cats received prednisolone, 24-hour urine pH was lower and 24-hour urine excretion of creatinine, magnesium, phosphate, and potassium was higher than when cats received placebo. No significant difference was found in urinary relative supersaturation for calcium oxalate (CaOx) or struvite between treatment groups. Prednisolone administration did not induce diuresis, nor was it associated with increased calcium excretion or urinary saturation for CaOx in these healthy cats. Results of this study, however, should not be extrapolated to cats that form CaOx uroliths associated with idiopathic hypercalcemia.

Keywords
  • Anti-Inflammatory Agents,
  • Calcium Oxalate,
  • Cat Diseases,
  • Cats,
  • Female,
  • Magnesium Compounds,
  • Phosphates,
  • Prednisolone,
  • Urinalysis,
  • Urinary Calculi
Disciplines
Publication Date
Winter 2007
Citation Information
N Geyer, Joe Bartges, C A Kirk, S Cox, et al.. "Influence of prednisolone on urinary calcium oxalate and struvite relative supersaturation in healthy young adult female domestic shorthaired cats" Veterinary Therapeutics Vol. 8 Iss. 4 (2007)
Available at: http://works.bepress.com/joe_bartges/8/