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Article
Open-source wax RepRap 3-D printer for rapid prototyping paper-based microfluidics
Journal of Laboratory Automation
  • Joshua M. Pearce, Michigan Technological University
  • Gerald C. Anzalone, Michigan Technological University
  • C. L. Heldt, Michigan Technological University
Document Type
Article
Publication Date
8-1-2016
Abstract
The open-source release of self-replicating rapid prototypers (RepRaps) has created a rich opportunity for low-cost distributed digital fabrication of complex 3-D objects such as scientific equipment. For example, 3-D printable reactionware devices offer the opportunity to combine open hardware microfluidic handling with lab-on-a-chip reactionware to radically reduce costs and increase the number and complexity of microfluidic applications. To further drive down the cost while improving the performance of lab-on-a-chip paper-based microfluidic prototyping, this study reports on the development of a RepRap upgrade capable of converting a Prusa Mendel RepRap into a wax 3-D printer for paper-based microfluidic applications. An open-source hardware approach is used to demonstrate a 3-D printable upgrade for the 3-D printer, which combines a heated syringe pump with the RepRap/Arduino 3-D control. The bill of materials, designs, basic assembly, and use instructions are provided, along with a completely free and open-source software tool chain. The open-source hardware device described here accelerates the potential of the nascent field of electrochemical detection combined with paper-based microfluidics by dropping the marginal cost of prototyping to nearly zero while accelerating the turnover between paper-based microfluidic designs.
Publisher's Statement

© 2016 Society for Laboratory Automation and Screening. Publisher's version of record: https://dx.doi.org/10.1177/2211068215624408

Citation Information
Joshua M. Pearce, Gerald C. Anzalone and C. L. Heldt. "Open-source wax RepRap 3-D printer for rapid prototyping paper-based microfluidics" Journal of Laboratory Automation Vol. 21 Iss. 4 (2016) p. 510 - 516
Available at: http://works.bepress.com/jmpearce/131/