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Na/K-ATPase Signaling and Salt Sensitivity: The Role of Oxidative Stress
Biochemistry and Microbiology
  • Jiang Liu, Marshall University
  • Yanling Yan, Marshall University
  • Ying Nie, Marshall Uinversity
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Other than genetic regulation of salt sensitivity of blood pressure, many factors have been shown to regulate renal sodium handling which contributes to long-term blood pressure regulation and have been extensively reviewed. Here we present our progress on the Na/K-ATPase signaling mediated sodium reabsorption in renal proximal tubules, from cardiotonic steroids-mediated to reactive oxygen species (ROS)-mediated Na/K-ATPase signaling that contributes to experimental salt sensitivity.

Copyright © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (

Citation Information
Liu J, Yan Y, Nie Y, Shapiro JI. Na/K-ATPase signaling and salt sensitivity: The role of oxidative stress. Antioxidants. 2017;6(1):14.