Skip to main content
Article
Electrophoretic Transport of Biomolecules through Carbon Nanotube Membranes
Langmuir (2011)
  • Xinghua Sun, University of Kentucky
  • Xin Su, University of Kentucky
  • Ji Wu, Georgia Southern University
  • Bruce J. Hinds, University of Kentucky
Abstract

Electrophoretic transport of proteins across electrochemically oxidized multi-walled carbon nanotube (MWCNT) membranes has been investigated. A small charged protein, lysozyme, was successfully pumped across MWCNT membranes by an electric field while rejecting larger bovine serum albumin (BSA). Transport of lysozome was reduced by a factor of about 30 in comparison to bulk mobility and consistent with the prediction for hindered transport. Mobilities between 0.33 and 1.4 × 10−9 m2 V−1 s−1 were observed and are approximately 10-fold faster than comparable ordered nanoporous membranes and consistent with continuum models. For mixtures of BSA and lysozyme, complete rejection of BSA is seen with electrophoretic separations.

Keywords
  • Electrophoretic Transport,
  • Carbon Nanotube,
  • BSA
Disciplines
Publication Date
2011
Publisher Statement
Must obtain written permission from editor/12 month embargo & must obtain written permission from editor confirming posting does not conflict prior publication policies
Citation Information
Xinghua Sun, Xin Su, Ji Wu, and Bruce J. Hinds. "Electrophoretic Transport of Biomolecules through Carbon Nanotube Membranes" Langmuir 27.6 (2011): 3150-3156. doi:10.1021/la104242p