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Electrophoretic Transport of Biomolecules through Carbon Nanotube Membranes
Langmuir (2011)
  • Xinghua Sun, University of Kentucky
  • Xin Su, University of Kentucky
  • Ji Wu, Georgia Southern University
  • Bruce J. Hinds, University of Kentucky

Electrophoretic transport of proteins across electrochemically oxidized multi-walled carbon nanotube (MWCNT) membranes has been investigated. A small charged protein, lysozyme, was successfully pumped across MWCNT membranes by an electric field while rejecting larger bovine serum albumin (BSA). Transport of lysozome was reduced by a factor of about 30 in comparison to bulk mobility and consistent with the prediction for hindered transport. Mobilities between 0.33 and 1.4 × 10−9 m2 V−1 s−1 were observed and are approximately 10-fold faster than comparable ordered nanoporous membranes and consistent with continuum models. For mixtures of BSA and lysozyme, complete rejection of BSA is seen with electrophoretic separations.

  • Electrophoretic Transport,
  • Carbon Nanotube,
  • BSA
Publication Date
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Citation Information
Xinghua Sun, Xin Su, Ji Wu, and Bruce J. Hinds. "Electrophoretic Transport of Biomolecules through Carbon Nanotube Membranes" Langmuir 27.6 (2011): 3150-3156. doi:10.1021/la104242p