With the Hispanic population considered the largest and fastest growing minority population, Hispanic health care needs will continue to place significant demands on our current system. Increasing the number of Hispanic nurses has become a priority. However, Latinos continue to account for only a small percentage of those enrolled in nursing programs. High attrition rates also negatively affect the number of Hispanic graduates. A more in-depth investigation of this complex issue may lead to increased awareness and understanding of the obstacles. This meta-synthesis aims to identify facilitators and barriers for Hispanic nursing students along their journey to success.