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Article
An Internet-based Controlled Trial Aimed to Improve Osteoporosis Prevention among Chronic Glucocorticoid Users
University of Massachusetts Medical School Faculty Publications
  • Amy H. Warriner, University of Alabama at Birmingham
  • Ryan C. Outman, University of Alabama at Birmingham
  • Jeroan J. Allison, University of Massachusetts Medical School
  • Jeffrey R. Curtis, University of Alabama at Birmingham
  • Nathan J. Markward, Express Scripts
  • David T. Redden, University of Alabama at Birmingham
  • Monika M. Safford, University of Alabama at Birmingham
  • Eric J. Stanek, Novartis Pharmaceuticals Corporation
  • Amy R. Steinkellner, Express Scripts
  • Kenneth G. Saag, University of Alabama at Birmingham
UMMS Affiliation
Department of Quantitative Health Sciences
Publication Date
8-1-2015
Document Type
Article
Subjects
Adult; Aged; Aged, 80 and over; Bone Density; Female; Glucocorticoids; Humans; Middle Aged; Osteoporosis
Abstract
OBJECTIVE: To address the low prevention and treatment rates for those at risk of glucocorticoid-induced osteoporosis (GIOP), we evaluated the influence of a direct-to-patient, Internet-based educational video intervention using "storytelling" on rates of antiosteoporosis medication use among chronic glucocorticoid users who were members of an online pharmacy refill service. METHODS: We identified members who refilled > /= 5 mg/day of prednisone (or equivalent) for 90 contiguous days and had no GIOP therapy for > /= 12 months. Using patient stories, we developed an online video addressing risk factors and treatment options, and delivered it to members refilling a glucocorticoid prescription. The intervention consisted of two 45-day "Video ON" periods, during which the video automatically appeared at the time of refill, and two 45-day "Video OFF" periods, during which there was no video. Members could also "self-initiate" watching the video by going to the video link. We used an interrupted time series design to evaluate the effectiveness of this intervention on GIOP prescription therapies over 6 months. RESULTS: Among 3017 members (64.8%) exposed to the intervention, 59% had measurable video viewing time, of which 3% "self-initiated" the video. The GIOP prescription rate in the "Video ON" group was 2.9% versus 2.7% for the "Video OFF" group. There was a nonsignificant trend toward greater GIOP prescription in members who self-initiated the video versus automated viewing (5.7% vs 2.9%, p = 0.1). CONCLUSION: Among adults at high risk of GIOP, prescription rates were not significantly affected by an online educational video presented at the time of glucocorticoid refill. ClinicalTrials.gov Identifier: NCT01378689.
Rights and Permissions
Citation: J Rheumatol. 2015 Aug;42(8):1478-83. doi: 10.3899/jrheum.141238. Epub 2015 Jul 1. Link to article on publisher's site
Related Resources
Link to Article in PubMed
PubMed ID
26136484
Citation Information
Amy H. Warriner, Ryan C. Outman, Jeroan J. Allison, Jeffrey R. Curtis, et al.. "An Internet-based Controlled Trial Aimed to Improve Osteoporosis Prevention among Chronic Glucocorticoid Users" Vol. 42 Iss. 8 (2015) ISSN: 0315-162X (Linking)
Available at: http://works.bepress.com/jeroan_allison/234/