The purpose of this study was to provide preliminary evidence of the criterion-related validity of curriculum-based measurement (CBM) for reading, mathematics, and written expression with postsecondary students with intellectual and developmental disabilities (ID). The participants included 41 postsecondary students with ID enrolled in a 2-year certificate program at a large Midwestern university. CBMs were administered to participants using standardized procedures, and results were compared with performance on the Woodcock–Johnson Tests of Achievement. Descriptive statistics were calculated as were bivariate correlations between CBM measures and the content-appropriate criterion measure. Results are discussed in terms of the potential use of CBMs as indicators of academic performance for postsecondary students with ID.