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Article
Genome Wide Association Studies for Residual Feed Intake Traits in Pigs
Animal Industry Report
  • Suneel Onteru, Iowa State University
  • Danielle Gorbach, Iowa State University
  • Jennifer M. Young, Iowa State University
  • Dorian J. Garrick, Iowa State University
  • Jack C.M. Dekkers, Iowa State University
  • Max F. Rothschild, Iowa State University
Extension Number
ASL R2816
Publication Date
2013
Topic
Swine
Summary and Implications

Residual feed intake (RFI), a measure of feed efficiency, is the difference between observed feed intake and the expected feed requirements computed based ongrowth and maintenance of the pig. Efficient animals with low RFI can be selected at an early age with genetic markers. Hence, the present study in 1400 pigs used several statistical methods to find the associations between more than 50,000 genetic markers and RFI, and its related traits such as average daily feed intake (ADFI), average daily gain (ADG), back fat (BF) and loin muscle area (LMA). Associations were observed for a combination of genetic markers on chromosomal regions containing insulin release genes (e.g., GLP1R, CDKAL, SGMS1) with RFI and ADFI, energy balance (e.g., MC4R, PGM1, GPR81) and muscle growth related genes (e.g., TGFB1) with ADG, fat related genes (e.g., ACOXL, AEBP1) with BF and skeletal muscle development genes (e.g., KLHL31) with LMA. Overall, these studies identified important chromosomal regions for further scrutiny to consider them for selection of pigs for RFI and its related traits.

Copyright Holder
Iowa State University
Language
en
Citation Information
Suneel Onteru, Danielle Gorbach, Jennifer M. Young, Dorian J. Garrick, et al.. "Genome Wide Association Studies for Residual Feed Intake Traits in Pigs" (2013)
Available at: http://works.bepress.com/jennifer_young/16/