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Evaluating the Role of Compression Stockings in Preventing Post thrombotic Syndrome: A Review of the Literature
Meyers Primary Care Institute Publications and Presentations
  • Abir O. Kanaan, University of Massachusetts Medical School
  • Jayne E. Lepage, Massachusetts College of Pharmacy and Health Sciences
  • Shabdis Djazayeri, Massachusetts College of Pharmacy and Health Sciences
  • Jennifer L. Donovan, University of Massachusetts Medical School
UMMS Affiliation
Meyers Primary Care Institute
Date
1-1-2012
Document Type
Article
Medical Subject Headings
Compression Bandages; Postthrombotic Syndrome
Abstract

Background. Postthrombotic syndrome (PTS) is a burdensome and costly complication of deep vein thrombosis (DVT). Up to 50% of patients with DVT will develop the disease within two years following the diagnosis of acute DVT. Various risk factors for developing PTS have been identified and different modalities have been used to prevent its development. Compression stockings have been studied for the prevention of PTS in patients diagnosed with proximal DVT.

Methods. MEDLINE and EMBASE databases were searched to identify relevant original articles.

Results. Several trials including two metaanalyses have examined the role of compression stockings for the prevention of PTS. Although most trials showed significant reduction in the development of PTS with the use of compression stockings, limitations in study design prevent the generalizability of the data. Two studies supported an individualized tailored duration especially in patients at low risk for developing the syndrome. A randomized double-blind placebo-controlled trial involving 800 patients is currently ongoing and may confirm the results of older studies.

Conclusions. Clinical trials support the use of compression stockings in patients diagnosed with proximal DVT for the prevention of PTS.

Comments

Citation: Abir O. Kanaan, Jayne E. Lepage, Shabdis Djazayeri, and Jennifer L. Donovan, “Evaluating the Role of Compression Stockings in Preventing Post thrombotic Syndrome: A Review of the Literature,” Thrombosis, vol. 2012, Article ID 694851, 9 pages, 2012. doi:10.1155/2012/694851. Link to article on publisher's website

Copyright © 2012 Abir O. Kanaan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Related Resources
Link to article in PubMed
PubMed ID
22315680
Citation Information
Abir O. Kanaan, Jayne E. Lepage, Shabdis Djazayeri and Jennifer L. Donovan. "Evaluating the Role of Compression Stockings in Preventing Post thrombotic Syndrome: A Review of the Literature" Vol. 2012 (2012) ISSN: 2090-1496
Available at: http://works.bepress.com/jennifer_donovan/12/